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KMID : 0360419690050020061
Korean Journal of Pharmacology
1969 Volume.5 No. 2 p.61 ~ p.66
The Effects of Various Drugs on Rat Submaxillary Gland
ÚÓÒÍýì/Park, No Hi
ÚÓùÓçµ/Îýý÷âª/åûê¡ÔÄ/Lim, Han Young/Koo, Hi Soo/Lyo, Woon Don
Abstract
In order to investigate the effect of autonomic nervous system on salivary gland, the authors have observed the effects of various drugs acting on the autonomic nervous system to the rat submaxillary gland by comparing the changes of gland weight, the amylase activity and various electrolyte contents with control group.
The results are as follows;
1. The pilocarpine, physostigmine, norepinephrine, atropine and DMPP increased the rat submaxillary gland weight.
2. The amylase activities of rat submaxillary gland were increased by pilocarpine, physostigmine and norepinephrine, but decreased by atropine and DMPP.
3. Calcium contents of rat submaxillary gland were highly increased by pilocarpine and physostigmine, but slightly increased by norepinephrine.
4. Magnesium contents of rat submaxillary gland were increased by DMPP, but decreased by Pilocarpine, physostigmine and norepinephrine.
5. Sodium contents of rat submaxillary gland were increased by pilocarpine, physostigmine, norepinephrine and DMPP, but decreased by atropine.
6. Potassium contents of rat submaxillary gland were highly increased by atropine, and slightly increased by DMPP and norepinephrine, but decreased by pilocarpine and physostigmine.
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